Cozaar

(Losartan)

ApprovedSmall molecule

Losartan is used to treat high blood pressure and to help protect the kidneys in people with diabetes. It works by relaxing blood vessels so blood can flow more easily through them.[2] Cozaar is currently approved and in use across 65 indications[4].[1]

Cozaar is one of 1242 small molecule programs targeting Pancreatic Cancer. It is currently in Approved.

Indications

198

Total Trials

Active Trials

1,241

Competitors

FDA Applications

NDA/BLA/ANDA regulatory filings

Patents

Pipeline

Status by Indication[4][1]

Indication

Pancreatic CancerActive, not recruiting

Metabolic SyndromeActive, not recruiting

EmphysemaActive, not recruiting

Endothelial DysfunctionActive, not recruiting

HyperuricemiaActive, not recruiting

Type 2 Diabetes MellitusActive, not recruiting

Vestibular SchwannomaActive, not recruiting

Primary HyperoxaluriaApproved

Sickle Cell DiseaseApproved

HIV InfectionApproved

Pancreatic CancerPhase 2

Active, not recruiting

Metabolic SyndromeApproved

Active, not recruiting

EmphysemaApproved

Active, not recruiting

Endothelial DysfunctionApproved

Active, not recruiting

HyperuricemiaApproved

Active, not recruiting

Type 2 Diabetes MellitusApproved

Active, not recruiting

Vestibular SchwannomaPhase 2

Active, not recruiting

Primary HyperoxaluriaApproved

Approved

Sickle Cell DiseaseApproved

Approved

HIV InfectionApproved

Approved

Showing 10 of 64 indications

Competition

Competitive Landscape

449 competitors in Non-Small Cell Lung Cancer

#DrugCompanyPhaseTrials

Cozaar

OOrganon and Co

Approved

1 2

Augtyro

KKaruna Therapeutics, Inc., a Bristol Myers Squibb company

Phase 3

1 3

SKB264

SSichuan Kelun-Biotech Biopharmaceutical Co., Ltd.

Phase 3

5 4

QL2107

Qilu Pharmaceutical Co., Ltd.

Phase 3

1 5

Second-Line Systemic Therapy

SSun Yat-sen University

Phase 3

1 6

Remeron

OOrganon and Co

Preclinical

1 7

Valemetostat Tosylate

Daiichi Sankyo

Preclinical

1 8

Aqupla

Jiangsu Simcere Pharmaceutical Co., Ltd.

Preclinical

—9

Ftorafur

TThe First Affiliated Hospital with Nanjing Medical University

Preclinical

—10

Vibramycin

PPfizer's Upjohn has merged with Mylan to form Viatris Inc.

Preclinical

—

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q4 2026

Recruiting

Obesity, Morbid

NCT03519893

Phase 2Active, not recruiting

Vestibular Schwannoma

NCT01199978

Phase 2Active, not recruiting

Pancreatic Adenocarcinoma

NCT05077800

ApprovedRecruiting

Cardiovascular Diseases

NCT04715568

Q1 2027

Phase 1Not yet recruiting

Hypertension

NCT07784621

N/ARecruiting

Fibrosis

NCT07449000

Clinical

Trials by Indication[1]

Hypertension17 trials

An Efficacy and Safety Study in Children 6 to Less Than 18 Years of Age With Hypertension

Completed·AArbor Pharmaceuticals, Inc.·Phase 3·NCT02235909·377 enrolled

Contribution of Angiotensin II to Supine Hypertension in Autonomic Failure

Terminated·VVanderbilt University·Phase 1·NCT01292694·12 enrolled

Study to Evaluate the Effect on Improvement of LVH by the Control of BP in Hypertension Patients With AV Disease

Completed· Hanmi Pharmaceutical Company Limited logo

Hanmi Pharmaceutical Company Limited·Phase 4·NCT03666351·128 enrolled

Show 14 more trials

A Study To Evaluate The Efficacy Of Eplerenone Compared With Losartan For The Treatment Of Patients With Mild To Moderate Hypertension

Terminated· Pfizer logo

Pfizer·Phase 2·NCT00649311·248 enrolled

N-of-1 Trials In Children With Hypertension

Completed·TThe University of Texas Health Science Center, Houston·Phase 4·NCT03461003·49 enrolled

Treatment of Supine Hypertension in Autonomic Failure

Completed·VVanderbilt University·Phase 1·NCT00223717·152 enrolled

Efficacy and Safety Evaluating Study to Compare Kanarb (Fimasartan) and Cozaar® (Losartan) in Adult Patients With Grade I-II Arterial Hypertension

Completed·RR-Pharm·Phase 3·NCT02248961·179 enrolled

ACES - ACE Inhibitors Combined With Exercise for Seniors With Hypertension

Completed·UUniversity of Alabama at Birmingham·Phase 2·NCT03295734·223 enrolled

Diuretics and Angiotensin-Receptor Blocker Agents in Patients With Stage I Hypertension

Completed·HHospital de Clinicas de Porto Alegre·Phase 3·NCT00971165·655 enrolled

Olmesartan Medoxomil in Hypertension and Renal Impairment

Completed·SSankyo Pharma Gmbh·Phase 3·NCT00151827·393 enrolled

Ambulatory vs Office BP Management Usual Care for Diagnosing and Managing Hypertension: A Pilot Study

Completed·AAnthony J Viera, MD, MPH·N/A·NCT02121041·28 enrolled

Losartan/Amlodipine on Hemodynamics Parameters and Arterial Stiffness in Arterial Hypertension

Unknown status·CCentro Universitario de Ciencias de la Salud, Mexico·Phase 4·NCT03626259·28 enrolled

A Phase 3 Study to Compare the Efficacy and Safety of Co-administered HGP0608, HGP0904 and HCP1306 Versus HCP1701 in Patients With Hypertension and Dyslipidemia

Completed· Hanmi Pharmaceutical Company Limited logo

Hanmi Pharmaceutical Company Limited·Phase 3·NCT04074551·145 enrolled

Prevention of Diabetes and Hypertension

Terminated·IIstituto Auxologico Italiano·Phase 4·NCT00456963·3,000 enrolled

Clinical Study to Evaluate the Antihypertensive Efficacy and Safety of Fimasartan in Hypertension Patients

Completed· Boryung Pharmaceutical Co., Ltd logo

Boryung Pharmaceutical Co., Ltd·Phase 3·NCT00922480·506 enrolled

An Open-Label, Multiple-oral Dosing, Phase 1 Clinical Trial to Evaluate the Safety and the Pharmacokinetic Drug-Drug Interaction Between HUC2A-752-A and HUC2A-752-B in Healthy Adults

Not yet recruiting·HHuons Co., Ltd.·Phase 1·NCT07784621·30 enrolled

Comparative Effectiveness of Dual Antihypertensive Regimens in Patients After Percutaneous Coronary Intervention

Recruiting·NNational Medical Research Center for Therapy and Preventive Medicine·Preclinical·NCT07683585·207 enrolled

ART10 trials

Atacand (Candesartan) Real Life Study

Completed· AstraZeneca logo

AstraZeneca··NCT00620178·14,000 enrolled

The Effect of Losartan on Cephalexin

Recruiting·AAleksi Tornio·Phase 1·NCT07300670·12 enrolled

The Effects of Losartan on Social Reward

Unknown status·UUniversity of Electronic Science and Technology of China·N/A·NCT04604756·90 enrolled

Show 7 more trials

Losartan and Emotion Processing

Unknown status·UUniversity of Electronic Science and Technology of China·N/A·NCT03396523·70 enrolled

Comparison of the Role of Losartan Alone vs Hydrochlorothiazide Plus Losartan

Not yet recruiting·RRESnTEC, Institute of Research·N/A·NCT06491940·234 enrolled

The Effects of Losartan on Reward Reinforcement Learning

Unknown status·UUniversity of Electronic Science and Technology of China·N/A·NCT04604938·60 enrolled

the Pharmacokinetic Profiles of Losartan With DW1029M

Completed·DDong Wha Pharmaceutical Co. Ltd.·Phase 1·NCT02212769·12 enrolled

The Effects of Losartan on Emotion Processing

Unknown status·UUniversity of Electronic Science and Technology of China·N/A·NCT04606212·90 enrolled

Losartan Modulates Neural Responses to Looming Visual Stimuli: An Eye-tracking Study

Recruiting·UUniversity of Electronic Science and Technology of China·N/A·NCT06329076·80 enrolled

Pioglitazone and Losartan Provides Additional Renoprotection

Completed·SShanghai Jiao Tong University School of Medicine·N/A·NCT00364988·60 enrolled

COVID-199 trials

Study of Open Label Losartan in COVID-19

Completed·UUniversity of Kansas Medical Center·Phase 1·NCT04335123·34 enrolled

Myocardial Protection in Patients With Post-acute Inflammatory Cardiac Involvement Due to COVID-19

Active, not recruiting·VValentina Puentmann·Phase 3·NCT05619653·279 enrolled

Losartan for Patients With COVID-19 Requiring Hospitalization

Completed·UUniversity of Minnesota·Phase 2·NCT04312009·205 enrolled

Show 6 more trials

Losartan for Patients With COVID-19 Not Requiring Hospitalization

Completed·UUniversity of Minnesota·Phase 2·NCT04311177·117 enrolled

Host Response Mediators in Coronavirus (COVID-19) Infection - Is There a Protective Effect of Losartan and Other ARBs on Outcomes of Coronavirus Infection?

Terminated·UUniversity of British Columbia·Phase 3·NCT04606563·341 enrolled

The Fleming [FMTVDM] Directed CoVid-19 Treatment Protocol

Completed·TThe Camelot Foundation·Phase 2/3·NCT04349410·1,800 enrolled

COVID MED Trial - Comparison Of Therapeutics for Hospitalized Patients Infected With COVID-19

Terminated·BBassett Healthcare·Phase 2/3·NCT04328012·15 enrolled

Coronavirus Response - Active Support for Hospitalised Covid-19 Patients

Withdrawn·LLondon School of Hygiene and Tropical Medicine·Phase 3·NCT04343001

Early Treatment With Ivermectin and LosarTAN for Cancer Patients With COVID-19 Infection

Terminated·IInstituto do Cancer do Estado de São Paulo·Phase 2·NCT04447235·77 enrolled

Essential Hypertension8 trials

Efficacy and Safety of Amlodipine and Losartan in Patients With Essential Hypertension

Completed· Hanmi Pharmaceutical Company Limited logo

Hanmi Pharmaceutical Company Limited·Phase 2·NCT00942344·320 enrolled

A Phase 2 Study to Assess Dose-response Relationship of HCP1803 in Patients With Essential Hypertension

Completed· Hanmi Pharmaceutical Company Limited logo

Hanmi Pharmaceutical Company Limited·Phase 2·NCT03897868·248 enrolled

Intensive Vasodilator Therapy in Patients With Essential Hypertension

Completed·—·Phase 4·NCT01180413·48 enrolled

Show 5 more trials

Effect of Losartan on Retinal Endothelial Function in Patients With Essential Hypertension

Withdrawn·UUniversity of Erlangen-Nürnberg Medical School·Phase 2/3·NCT00152633

MK-0954A in Japanese Patients With Essential Hypertension Not Adequately Controlled With Losartan (MK-0954A-352)

Completed·OOrganon and Co·Phase 3·NCT01307046·336 enrolled

Efficacy and Safety of HL-040XC in Essential Hypertension and Hyperlipidemia

Completed·HHanAll BioPharma Co., Ltd.·Phase 3·NCT01541943·356 enrolled

Efficacy/Safety of Amlodipine Plus Losartan Versus Losartan in Patients With Essential Hypertension

Completed· Hanmi Pharmaceutical Company Limited logo

Hanmi Pharmaceutical Company Limited·Phase 3·NCT00940680·142 enrolled

A Study on Molecular Genetics of Drug Responsiveness in Essential Hypertension

Completed·HHelsinki University Central Hospital·Phase 4·NCT03276598·233 enrolled

Nephropathy7 trials

The Effects of Mycophenolate Mofetil (MMF) on Renal Outcomes in Advanced Immunoglobulin A (IgA) Nephropathy Patients

Completed·FFan Fan Hou·N/A·NCT01854814·238 enrolled

A Prospective, Randomised, Double-blind, Double-dummy, Forced-titration, Multicentre, Parallel Group, One Year Treatment Trial to Compare Telmisartan (MICARDIS) 80 mg Versus Losartan (COZAAR) 100 mg, in Hypertensive Type 2 Diabetic Patients With Overt Nephropathy (AMADEO Study)

Completed· Boehringer Ingelheim logo

Boehringer Ingelheim·Phase 4·NCT00168857·860 enrolled

Losartan to Reverse Sickle Nephropathy

Completed·—·Phase 2·NCT01479439·36 enrolled

Show 4 more trials

Efficacy and Safety of Losartan in Children With Ig A Nephropathy

Completed·SSeoul National University Hospital·Phase 3·NCT02232776·37 enrolled

Add-on Pentoxifylline to Losartan Versus Increasing Dose of Losartan on NT-PRO BNP in Type 2 Diabetics With Nephropathy

Completed·TTehran University of Medical Sciences·Phase 4·NCT03006952·59 enrolled

Angiotensin II Blockade for Chronic Allograft Nephropathy

Completed·UUniversity of Minnesota·Phase 4·NCT00067990·153 enrolled

VA NEPHRON-D: Diabetes iN Nephropathy Study

Terminated·UUS Department of Veterans Affairs·Phase 3·NCT00555217·1,448 enrolled

102 more indications

Hypertensive7 trials

PPARgamma Activation by Losartan in Hypertensive Patients: The Importance of Losartan-Metabolites

Unknown status·GGerman Heart Institute··NCT00561327

Comparison Between Losartan and Benazepril in Diabetic Hypertensive Patients Not Controlled by Amlodipine

Completed·HHospital Universitario Pedro Ernesto·Phase 4·NCT01603940·30 enrolled

Antihypertensive Effect of Rostafuroxin Compared With Losartan in Hypertensive Patients Bearing Specified Gene Mutations

Unknown status·RRostaQuo S.p.A.·Phase 2·NCT01320397·240 enrolled

Show 4 more trials

Effects Of Losartan On Myocardial Structure In Diabetic Hypertensive Patients With Left Ventricular

Unknown status·UUniversity of Pavia·Phase 3·NCT00659451·100 enrolled

Telmisartan With or Without Hydrochlorothiazide (HCTZ) Compared With Losartan With or Without HCTZ in Mild to Moderate Hypertensive Patients

Completed· Boehringer Ingelheim logo

Boehringer Ingelheim·Phase 4·NCT02172586·363 enrolled

Antihypertensive Effect of Different Doses of Rostafuroxin in Comparison With Losartan

Completed·WWindtree Therapeutics·Phase 2·NCT03217825·240 enrolled

Telmisartan and Losartan in Hypertensive IGT

Completed·MMedical University of Graz·Phase 4·NCT00407862·24 enrolled

Marfan syndrome5 trials

Randomized, Double-blind Study for the Evaluation of the Effect of Losartan Versus Placebo on Aortic Root Dilatation in Patients With Marfan Syndrome Under Treatment With Beta-blockers

Completed·UUniversity Hospital, Ghent·Phase 3·NCT00782327·22 enrolled

Atenolol Versus Losartan in the Prevention of Progressive Dilation of the Aorta in Marfan Syndrome

Unknown status·—·Phase 3·NCT01145612·140 enrolled

Effects of Losartan Versus Atenolol on Aortic and Cardiac Muscle Stiffness in Adults With Marfan Syndrome

Completed·—·Phase 3·NCT00723801·40 enrolled

Show 2 more trials

Losartan Versus Atenolol for the Treatment of Marfan Syndrome

Completed·UUniversity of British Columbia·Phase 2·NCT00593710·17 enrolled

Study of the Efficacy of Losartan on Aortic Dilatation in Patients With Marfan Syndrome

Terminated·AAssistance Publique - Hôpitaux de Paris·Phase 3·NCT00763893·303 enrolled

Diabetic Nephropathy5 trials

Renoprotection in Early Diabetic Nephropathy in Pima Indians

Completed·NNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)·Phase 3·NCT00340678·170 enrolled

Resveratrol's Effects in Diabetic Nephropathy

Completed·SShiraz University of Medical Sciences·Phase 1·NCT02704494·60 enrolled

Patiromer in the Treatment of Hyperkalemia in Patients With Hypertension and Diabetic Nephropathy (AMETHYST-DN)

Completed·RRelypsa, Inc.·Phase 2·NCT01371747·324 enrolled

Show 2 more trials

Adiponectin and Insulin Resistance in Diabetic Nephropathy

Completed·XXi'an Jiaotong University·N/A·NCT00774904·80 enrolled

Olmesartan Medoxomil and Diabetic Nephropathy

Completed·SSankyo Pharma Gmbh·Phase 3·NCT00362960·300 enrolled

Kidney Disease4 trials

Losartan for Sickle Cell Kidney Disease

Completed·EEmory University·Phase 1·NCT01989078·24 enrolled

Preventing Sickle Cell Kidney Disease

Terminated·UUniversity of Alabama at Birmingham·Phase 2·NCT02373241·1 enrolled

Azilsartan in Patients With Diabetic Kidney Disease and Hypertension

Unknown status·SSecond Affiliated Hospital, School of Medicine, Zhejiang University·N/A·NCT05753696·106 enrolled

Show 1 more trial

Improving Outcomes in Patients With Kidney Disease Due to Diabetes

Completed·NNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)·Phase 2·NCT00381134·92 enrolled

Fibrosis4 trials

Reversing Tissue Fibrosis to Improve Immune Reconstitution in HIV

Completed·UUniversity of Minnesota·Phase 2·NCT01852942·52 enrolled

Losartan Use to Mitigate Arthrofibrosis Following Total Join Arthroplasty

Withdrawn·NNYU Langone Health·Phase 4·NCT05157464

Losartan to Reduce Inflammation and Fibrosis Endpoints in HIV Trial

Completed·HHennepin Healthcare Research Institute·Phase 2·NCT02049307·108 enrolled

Show 1 more trial

Losartan for Corneal Fibrosis

Recruiting·UUniversidad Autonoma de Nuevo Leon·N/A·NCT07449000·46 enrolled

Fasting Conditions3 trials

Losartan 100 mg Tablet in Healthy Subjects Under Non-Fasting Conditions

Completed· Teva logo

Teva·Phase 1·NCT01124175·80 enrolled

Losartan 100 mg Tablets in Healthy Subjects Under Fasting Conditions

Completed· Teva logo

Teva·Phase 1·NCT01124162·80 enrolled

Non-interaction Study of Chlorthalidone and Losartan in Fixed Combination, in Healthy Subjects, Under Fasting Conditions

Completed·LLaboratorios Silanes S.A. de C.V.·Phase 1·NCT05090449·36 enrolled

Peritoneal Dialysis3 trials

Effect of Add-on Spironolactone to Losartan Versus Losartan Alone on Peritoneal Membrane Among Peritoneal Dialysis Patients

Unknown status·—·Phase 4·NCT03953950·84 enrolled

Nighttime Losartan in Continous Ambulatory Peritoneal Dialysis (NVCAPD)

Unknown status·FFifth Affiliated Hospital, Sun Yat-Sen University·Phase 4·NCT03692013·68 enrolled

Residual Renal Function Preservation in Peritoneal Dialysis Patients

Unknown status·SSecond Xiangya Hospital of Central South University·N/A·NCT02190318·96 enrolled

Cystic Fibrosis3 trials

Losartan and Inflammation in Cystic Fibrosis

Terminated·UUniversity of Miami·Phase 2·NCT03206788·7 enrolled

Effect of Losartan in Cystic Fibrosis (CF)-NIH Grant #133240

Active, not recruiting·UUniversity of Kansas Medical Center·Phase 1·NCT03435939·16 enrolled

Targeting Inflammation With Losartan to Improve Response to Modulator Therapy in Cystic Fibrosis.

Recruiting·UUniversity of Kansas Medical Center·Phase 2·NCT06364176·42 enrolled

Chronic Kidney Disease3 trials

Efficacy and Safety of Losartan in Pediatric Chronic Kidney Disease With Tubular Proteinuria

Completed·SSeoul National University Hospital·Phase 3·NCT02232763·58 enrolled

Pharmacokinetic Study in Patients With Chronic Kidney Disease and Healthy Volunteers

Completed·UUniversity of California, San Francisco·Phase 1·NCT01087749·24 enrolled

Aliskiren Combined With Losartan in Proteinuric, Non-diabetic Chronic Kidney Disease

Completed·TThe University of Hong Kong·Phase 4·NCT01150201·80 enrolled

Pancreatic Cancer3 trials

Losartan and Nivolumab in Combination With FOLFIRINOX and SBRT in Localized Pancreatic Cancer

Active, not recruiting·MMassachusetts General Hospital·Phase 2·NCT03563248·168 enrolled

GEM+Nab-Paclitaxel Plus Losartan Followed by Stereotactic Radiotherapy for Locally Advanced Pancreatic Cancer

Withdrawn·IIstituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS·Phase 2·NCT05861336

Proton w/FOLFIRINOX-Losartan for Pancreatic Cancer

Unknown status·MMassachusetts General Hospital·Phase 2·NCT01821729·50 enrolled

Heart Failure3 trials

Losartan in Decompensated Heart Failure

Completed·IInCor Heart Institute·Phase 4·NCT01857999·21 enrolled

Losartan in Prevention of Radiation-Induced Heart Failure

Unknown status·MMassachusetts General Hospital·Phase 1·NCT05607017·10 enrolled

Study to Evaluate Potential Decrease in Hospitalization Events, Time Between Events, and Increasing Longevity in Patients With Symptomatic Heart Failure (0954-948)

Completed·OOrganon and Co·Phase 3·NCT00090259·3,834 enrolled

Kidney Transplant3 trials

Telmisartan Versus Losartan in Kidney Transplantation

Completed· Mario Negri Institute for Pharmacological Research logo

Mario Negri Institute for Pharmacological Research·Phase 2·NCT01224860·20 enrolled

Influence of Aliskiren on Albuminuria After Kidney Transplantation

Completed·MMedical University of Gdansk·N/A·NCT02446548·18 enrolled

Cardiorenal Effecs of Losartan in Kidney Transplant Recipients

Unknown status·MMedical University of Gdansk··NCT05243446·740 enrolled

Idiopathic Pulmonary Fibrosis2 trials

Losartan in Treating Patients With Idiopathic Pulmonary Fibrosis

Completed·UUniversity of South Florida·N/A·NCT00879879·20 enrolled

Targeting Vascular Reactivity in Idiopathic Pulmonary Fibrosis

Terminated·AAlicia Gerke·Phase 2/3·NCT00981747·12 enrolled

Renal insufficiency2 trials

Long-Term Renoprotection of Optimal Antiproteinuric Doses of Benazepril and Losartan in Chronic Renal Insufficiency

Terminated·SSouthern Medical University, China·N/A·NCT00338091

Safety of Dual Blockage of Rennin-angiotensin System in Patients With Advanced Renal Insufficiency

Terminated·NNanfang Hospital, Southern Medical University·N/A·NCT00630708·309 enrolled

Type 2 Diabetes2 trials

Metformin's Effect on Drug Metabolism in Patients With Type 2 Diabetes

Terminated·UUniversity of Southern Denmark·Phase 1·NCT04504045·10 enrolled

Effects of Losartan on Insulin Sensitivity and Secretion in Type 2 Diabetes and Nephropathy

Completed·SShanghai Jiao Tong University School of Medicine·N/A·NCT00361023·25 enrolled

Atrial Fibrillation2 trials

The Effect of Losartan on Atrial Fibrillation (AF) Burden and Pacemaker Dependence in Patients With Sick Sinus Syndrome

Unknown status·—·N/A·NCT00647257·220 enrolled

PREvention of Atrial Fibrillation in patientS Undergoing thorAcic surGEry for Lung Cancer

Completed·EEuropean Institute of Oncology·Phase 3·NCT01281787·320 enrolled

Trial2 trials

Pilot Trial: the Safety and Feasibility of Losartan for Pulmonary Vein Stenosis

Suspended·TThe Hospital for Sick Children·Phase 1/2·NCT02769130·40 enrolled

Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial

Terminated·OOHSU Knight Cancer Institute·Phase 1·NCT03878524·2 enrolled

Blood Pressure2 trials

N-of-1 Trials for Blood Pressure Medications in Adults

Completed·—·Phase 1·NCT02744456·10 enrolled

Comparison of Blood Pressure Lowering Effect Between Fimasartan and Losartan

Unknown status·—·Phase 4·NCT02958631·40 enrolled

Insulin resistance2 trials

Effects of Losartan on Insulin Resistance in Patients With Heart Failure

Completed·TTottori University Hospital·Phase 4·NCT00663377·16 enrolled

Effect of Angiotensin Receptor Blockade on Insulin Resistance and Adipose Tissue Cytokines in Type 2 Diabetes

Completed·IInstitute for Clinical and Experimental Medicine·N/A·NCT01011062·23 enrolled

Tics2 trials

Ocsaar and CYP2C9 Ploymorphism, Is There a Connection Between Pharmacokinetics, Pharmacodynamics and Pharmacogenetics?

Unknown status·—·N/A·NCT00732966·30 enrolled

Study to Evaluate Effect of Belatacept on Pharmacokinetics of Inje Cocktail in Healthy Volunteers

Completed· Bristol-Myers Squibb logo

Bristol-Myers Squibb·Phase 4·NCT01766050·45 enrolled

Hypertrophic Cardiomyopathy2 trials

Effect of Losartan in Patients With Nonobstructive Hypertrophic Cardiomyopathy

Completed·MMassachusetts General Hospital·Phase 2·NCT01150461·20 enrolled

Inhibition of the Renin Angiotensin System With Losartan in Patients With Hypertrophic Cardiomyopathy

Completed·HHenning Bundgaard·Phase 2·NCT01447654·130 enrolled

Interaction2 trials

Phase 4, Vedolizumab-4002 Post-marketing, Disease-Drug-Drug Interaction Study

Withdrawn· Takeda logo

Takeda·Phase 4·NCT02760615

Pharmacokinetic Interactions of Losartan and Hydrochlorothiazide

Completed·—·N/A·NCT01858623·18 enrolled

Tachycardia1 trial

Local Vasoconstriction in Postural Tachycardia Syndrome

Completed·NNew York Medical College·Phase 1·NCT01210430·74 enrolled

Oxidative Stress1 trial

Pilot Study of Losartan and N-acetylcysteine as Inhibitors of Muscle Oxidative Stress in Elderly

Completed·TThe University of Texas Medical Branch, Galveston·Phase 1/2·NCT01384591·6 enrolled

Hyperuricemia1 trial

Non-Inferiority Study of Aliskiren vs Losartan in the Treatment of Hypertension With Hyperuricemia

Completed·—·Phase 4·NCT06718062·66 enrolled

NASH1 trial

Anti-Fibrotic Effects of Losartan In Nash Evaluation Study

Completed·NNewcastle-upon-Tyne Hospitals NHS Trust·Phase 3·NCT01051219·45 enrolled

Microvascular Function1 trial

Effects of Amlodipine and Other Blood Pressure Lowering Agents on Microvascular Function

Terminated·LLudwig-Maximilians - University of Munich·Phase 3·NCT03082014·101 enrolled

Advanced Solid Tumors1 trial

Pharmacokinetic Drug-drug Interaction Study of Encorafenib and Binimetinib on Probe Drugs in Patients With BRAF V600-mutant Melanoma or Other Advanced Solid Tumors

Completed· Pfizer logo

Pfizer·Phase 1·NCT03864042·56 enrolled

Peripheral Arterial Disease1 trial

Study to Evaluate the Effect of Simvastatin, Losartan and Pioglitazone on Patients With Peripheral Arterial Disease.

Completed·MMedtronic Endovascular·Phase 1·NCT00720577·164 enrolled

Peripheral Neuropathy1 trial

Prevention of Paclitaxel-induced Peripheral Neuropathy in Breast Cancer Patients

Completed·FFuture University in Egypt·Phase 2·NCT06135493·84 enrolled

Treatment1 trial

Study of Losartan in the Treatment of NAFLD in Children

Completed·—·Phase 2·NCT01913470·12 enrolled

Total Joint Arthroplasty1 trial

Losartan Use to Mitigate Arthrofibrosis Following Total Joint Arthroplasty

Withdrawn·NNYU Langone Health·Phase 4·NCT06333522

Myocardial fibrosis1 trial

Losartan for Diffuse Myocardial Fibrosis in Sickle Cell Disease

Recruiting·—·Phase 2·NCT05012631·24 enrolled

Neuropathy1 trial

Diabetic Autonomic Neuropathy and Left Ventricular Function

Completed·—·Phase 4·NCT05713396·59 enrolled

Survival1 trial

Fixed Dose Intervention Trial of New England Enhancing Survival in SMI Patients

Completed·MMclean Hospital·Phase 4·NCT02188121·227 enrolled

Adiponectin1 trial

Adiponectin in Obese Women With T2DN and Effects by RAS Blocker

Completed·SShanghai Jiao Tong University School of Medicine·N/A·NCT00561704·80 enrolled

Emotional Processing1 trial

The Effect of Losartan on Emotional Processing in Healthy Volunteers

Completed·UUniversity of Oxford·N/A·NCT03434054·30 enrolled

Chronic Hepatitis1 trial

Effects of Losartan on Hepatic Fibrogenesis in Chronic Hepatitis C

Completed·HHospital Clinic of Barcelona·Phase 4·NCT00298714·20 enrolled

Completed·SSharp HealthCare·Phase 4·NCT04340557·31 enrolled

Diabetes Mellitus1 trial

Aliskiren's Effect on Arterial Stiffness and Platelet Function in Patients With Diabetes Mellitus (DM)

Unknown status·—·N/A·NCT00732407·40 enrolled

Insulin Sensitivity1 trial

Treating the Endothelium to Restore Insulin Sensitivity

Completed·IIndiana University School of Medicine·N/A·NCT00402194·17 enrolled

IgA Nephropathy1 trial

Efficacy and Safety of Abelmoschus Manihot for IgA Nephropathy

Unknown status·CChen Xiangmei·Phase 4·NCT02231125·1,600 enrolled

Type 2 Diabetes Mellitus1 trial

Effect of Enalapril and Losartan Association Therapy on Proteinuria and Inflammatory Biomarkers in Diabetic Nephropathy: a Clinical Trial on Type 2 Diabetes Mellitus

Completed·UUniversity of Sao Paulo·Phase 4·NCT00419835·80 enrolled

ESS1 trial

Study of Inherited Changes of Receptors Located on Blood Vessels

Completed·NNational Heart, Lung, and Blood Institute (NHLBI)·Phase 1·NCT00001741·200 enrolled

Metabolic Syndrome1 trial

A Clinical Trial to Evaluate the Blood Pressure Control of Telmisartan or Losartan in Essential Hypertensive Patients With Metabolic Syndrome

Unknown status· Chong Kun Dang Pharmaceutical logo

Chong Kun Dang Pharmaceutical·Phase 4·NCT05843162·116 enrolled

Hypoxia1 trial

AT1R Blockade and Periodic Breathing During Sleep in Hypoxia

Completed·UUniversity of British Columbia·Phase 4·NCT03335904·14 enrolled

Biomarkers1 trial

ALiskiren or Losartan Effects on bioMARKers of Myocardial Remodeling

Completed· Novartis logo

Novartis·Phase 4·NCT01176032·74 enrolled

Fracture1 trial

Losartan to Improve Hip Microfracture

Terminated·SSteadman Philippon Research Institute·Phase 1/2·NCT04212650·1 enrolled

Obstructive Sleep Apnea1 trial

Study of Cardiovascular Disease and Obstructive Sleep Apnea

Completed·UUniversity of Wisconsin, Madison·Phase 2·NCT01637623·87 enrolled

Dilation1 trial

Nebivolol Versus Losartan Versus Nebivolol+Losartan Against Aortic Root Dilation in Genotyped Marfan Patients

Unknown status·FFondazione IRCCS Policlinico San Matteo di Pavia·Phase 3·NCT00683124·291 enrolled

Ovarian Cancer1 trial

Losartan and Paclitaxel in Platinum Resistant Ovarian Cancer

Not yet recruiting·MMassachusetts General Hospital·Phase 2·NCT07265739·27 enrolled

Head and Neck Squamous Cell Carcinoma1 trial

Losartan, Pembrolizumab and Stereotactic Body Radiation Therapy for the Treatment of Patients With Locally Recurrent, Refractory or Oligometastatic Head and Neck Squamous Cell Carcinoma

Recruiting·UUniversity of California, Davis·Phase 1·NCT06211335·24 enrolled

Cirrhosis1 trial

Prevention of Decompensation in Liver Cirrhosis

Unknown status·OOdense University Hospital·Phase 4·NCT00239096·100 enrolled

Post-Traumatic Stress Disorder1 trial

A Controlled Trial of Losartan in Posttraumatic Stress Disorder

Completed·UUniversity of California, San Diego·N/A·NCT02709018·149 enrolled

Non-Small Cell Lung Cancer1 trial

Losartan in Treating Pulmonary Fibrosis in Patients With Stage I, II, or III Non-Small Cell Lung Cancer

Withdrawn·UUniversity of South Florida·N/A·NCT00880386

Attention1 trial

The Effects of Losartan on Attention Control: An Eye-tracking Study

Recruiting·UUniversity of Electronic Science and Technology of China·N/A·NCT06329050·80 enrolled

Endothelial Dysfunction1 trial

A Randomized Clinical Trial To Study Losartan On Endothelial Dysfunction and Insulin Resistance In Obese Patients

Completed·—·Phase 4·NCT00675987·53 enrolled

Clinical Trial1 trial

Phase 1/2 Prospective Double-Blind Placebo-Controlled Randomized Clinical Trial of Losartan to Treat Grade II & III Hamstring Strains

Terminated·—·Phase 1/2·NCT02263729·8 enrolled

Vitamin D1 trial

Intervention Using Vitamin D for Elevated Urinary Albumin Treated With Losartan in Diabetes (IDEAL)

Terminated·WWeill Cornell Medical College in Qatar·Phase 2/3·NCT02410005·56 enrolled

Cardiovascular Disease1 trial

Evaluation of Losartan on Cardiovascular Disease in Patients With Mucopolysaccharidoses IV A and VI

Unknown status·HHospital de Clinicas de Porto Alegre·Phase 2·NCT03632213·10 enrolled

Ischemic stroke1 trial

The Effect of Losartan Versus Amlodipine-based Therapy in Ischemic Stroke (0954-338)(COMPLETED)

Completed·TTaipei Veterans General Hospital, Taiwan·Phase 4·NCT00754429·40 enrolled

Total Knee Arthroplasty1 trial

Mitigation of Arthrofibrosis After Total Knee Arthroplasty Using Losartan

Recruiting·SSteadman Philippon Research Institute·Phase 1/2·NCT06108063·120 enrolled

Arteriovenous Fistula1 trial

Attenuation of Cardiac Effects of Arteriovenous Fistula Creation With Losartan

Completed·MMelbourne Health·N/A·NCT00602004·52 enrolled

Cardiomyopathy1 trial

Cardiomyopathy in DMD: Lisinopril vs. Losartan

Completed·NNationwide Children's Hospital·N/A·NCT01982695·23 enrolled

Adenocarcinoma1 trial

Tissue Pharmacokinetics of Intraoperative Gemcitabine in Resectable Adenocarcinoma of the Pancreas

Terminated·MM.D. Anderson Cancer Center·Phase 1·NCT01276613·18 enrolled

Memory1 trial

Losartan Effects on Emotion-memory Interaction

Unknown status·UUniversity of Electronic Science and Technology of China·N/A·NCT04606225·60 enrolled

Osteoarthritis1 trial

Use of Senolytic and Anti-Fibrotic Agents to Improve the Beneficial Effect of Bone Marrow Stem Cells for Osteoarthritis

Active, not recruiting·SSteadman Philippon Research Institute·Phase 1/2·NCT04815902·100 enrolled

Tetralogy of Fallot1 trial

Right Ventricular Dysfunction in Tetralogy of Fallot: Inhibition of the Renin-angiotensin-aldosterone System

Unknown status·—·Phase 2·NCT02010905·120 enrolled

Efficacy and Safety1 trial

Efficacy and Safety of Telmisartan Compared With Losartan

Recruiting· Chong Kun Dang Pharmaceutical logo

Chong Kun Dang Pharmaceutical·Phase 4·NCT06431477·98 enrolled

Imaging1 trial

Imaging Perfusion Restrictions From Extracellular Solid Stress - An Open-label Losartan Study

Unknown status·KKyrre Eeg Emblem·Phase 2·NCT03951142·165 enrolled

Diabetic Macular Edema1 trial

Randomized Clinical Trial of Intravitreal Bevacizumab Versus Intravitreal Bevacizumab Combined With Losartan in the Treatment of Diabetic Macular Edema

Completed·TTehran University of Medical Sciences·Phase 2·NCT02663141·57 enrolled

Hermansky-Pudlak syndrome1 trial

Pilot Study of a Multi-Drug Regimen for Severe Pulmonary Fibrosis in Hermansky-Pudlak Syndrome

Terminated·NNational Human Genome Research Institute (NHGRI)·Phase 1/2·NCT00467831·3 enrolled

PTSD1 trial

Role of Sympathetic Overactivity and Angiotensin II in PTSD and CV

Suspended·EEmory University·Phase 2·NCT02560805·134 enrolled

Glioblastoma1 trial

Angiotensin II Receptor Blockers, Steroids and Radiotherapy in Glioblastoma

Completed·AAssistance Publique - Hôpitaux de Paris·Phase 3·NCT01805453·80 enrolled

Sleep Apnea1 trial

Losartan in Hypertensive Men and Women With Sleep Apnea Before and on Continuous Positive Airway Pressure (CPAP) Treatment

Completed·SSkaraborg Hospital·Phase 4·NCT00701428·90 enrolled

Efficacy1 trial

Efficacy of Losartan in Preventing Progression of COPD

Completed·JJohns Hopkins University·Phase 4·NCT00720226·106 enrolled

Valve Surgery1 trial

Effect of Losartan on the Neurohumoral Axis and Ventricular Remodeling of Patients With Severe Aortic Regurgitation Undergoing Valve Surgery.

Recruiting·VVitor Emer Egypto Rosa·Phase 4·NCT07099859·60 enrolled

Chronic Bronchitis1 trial

Effect of Losartan on Airway Mucociliary Dysfunction in Patients With COPD and Chronic Bronchitis

Terminated·UUniversity of Miami·Phase 4·NCT02416102·31 enrolled

Knee Injury1 trial

Losartan to Improve Outcomes After Multi-ligament Knee Injury

Recruiting·—·Phase 2·NCT06933706·90 enrolled

Hepatitis1 trial

Rosiglitazone Versus Rosiglitazone and Metformin Versus Rosiglitazone and Avandia in the Treatment of Nonalcoholic Steatohepatitis (NASH)

Unknown status·—·Phase 2·NCT00699036·165 enrolled

Inflammation1 trial

The ENRGISE (ENabling Reduction of Low-Grade Inflammation in SEniors) Pilot Study

Completed·UUniversity of Florida·Phase 2·NCT02676466·289 enrolled

Emphysema1 trial

Losartan Effects on Emphysema Progression

Completed·JJHSPH Center for Clinical Trials·Phase 4·NCT02696564·220 enrolled

Pulmonary Hypertension1 trial

Losartan Therapy in Pulmonary Hypertension

Completed·—·Phase 3·NCT00519870

Blood Pressure Variability1 trial

Comparision of Blood Pressure Variability Between Amlodipine and Losartan

Completed·WWonju Severance Christian Hospital·Phase 4·NCT01964079·144 enrolled

Left Ventricular Hypertrophy1 trial

Efficacy and Safety of Valsartan in Combination With Amlodipine Compared to Losartan Plus Hydrochlorothiazide in Patients With Hypertension and Left Ventricular Hypertrophy

Completed· Novartis logo

Novartis·Phase 3·NCT00446563·90 enrolled

Adult1 trial

A Study of Muscle Strength Maintenance in Older Adults

Completed·JJohns Hopkins University·Phase 2·NCT01989793·37 enrolled

Oral1 trial

Study to Use Oral Losartan to Decrease the Risk of Postoperative Scarring Following (ACL) Reconstruction

Not yet recruiting·RRush University Medical Center·Phase 4·NCT07135687·144 enrolled

Paraffinoma1 trial

Prevention of Kidney Stones Due to Paraffin Oil Induced Granuloma: A Prospective Interventional Study

Not yet recruiting·MMartin Blomberg Jensen·Preclinical·NCT07828002·100 enrolled

Coarctation of Aorta1 trial

A Phase III, Randomized, Double-Blind, Placebo Controlled Clinical Trial Evaluating the Benefits and Mechanism Of Action Of Angiotensin-II Receptor Blocker On Cardiovascular Remodeling In Patients With Repaired Coarctation Of Aorta

Recruiting·MMayo Clinic·Phase 3·NCT06150560·120 enrolled

Vestibular schwannoma1 trial

Hearing Outcomes Using Fractionated Proton Radiation Therapy for Vestibular Schwannoma

Active, not recruiting·MMassachusetts General Hospital·Phase 2·NCT01199978·30 enrolled

Pancreatic Adenocarcinoma1 trial

A Phase II Study of FOLFIRINOX Combined With the Glycogen Synthase Kinase-3 Beta (GSK-3 β) Inhibitor Elraglusib and the Transforming Growth Factor-β (TGF-β) Inhibitor Losartan in Patients With Untreated Metastatic Pancreatic Adenocarcinoma

Active, not recruiting·CColin D. Weekes, M.D., PhD·Phase 2·NCT05077800·70 enrolled

Osteosarcoma1 trial

A Phase I/Ib Study of Losartan in Combination With Sunitinib in the Treatment of Pediatric and Adult Patients With Relapsed or Refractory Osteosarcoma

Recruiting·UUniversity of Colorado, Denver·Phase 1·NCT03900793·41 enrolled

Glioblastoma (GBM)1 trial

Phase 1/2 Trial of a Combination Immunotherapy Treatment for Solid Tumors Including BreakVax ImmunoTreatment (Designed and Manufactured Per Patient), Chemotherapy and Anti PD-1 Therapy

Not yet recruiting·BBreakBio Corp·Preclinical·NCT07762716·10 enrolled

Cardiovascular Diseases1 trial

Occult Cardiovascular Disease With Chronic Exposure to Secondhand Tobacco Smoke

Recruiting·UUniversity of California, San Francisco·Approved·NCT04715568·100 enrolled

Triple Negative Breast Cancer (TNBC)1 trial

Phase 1/2 Trial of a Combination Immunotherapy Treatment for Solid Tumors Including BreakVax ImmunoTreatment (Designed and Manufactured Per Patient), Chemotherapy and Anti PD-1 Therapy

Not yet recruiting·BBreakBio Corp·Preclinical·NCT07762703·10 enrolled

Obesity, Morbid1 trial

Bariatric Surgery and Pharmacokinetics of Losartan: BAR-MEDS Losartan

Recruiting·NNorwegian University of Science and Technology··NCT03519893·12 enrolled

Obesity & Overweight1 trial

Comparative Evaluation of Rosuvastatin and Losartan Pharmacokinetics and the Associations Between Gut Microbiota Alterations and Changes in Systemic Drug Exposure in Patients Undergoing Roux-en-Y Gastric Bypass or Sleeve Gastrectomy

Not yet recruiting·HHospital das Clínicas de Ribeirão Preto·Preclinical·NCT07748273·60 enrolled

Borderline Resectable Pancreatic Adenocarcinoma1 trial

SHAPER: A Phase 1 Study of Losartan and Hypofractionated Radiation Therapy After Induction Chemotherapy for Borderline Resectable or Locally Advanced Pancreatic Cancer

Completed·UUniversity of Utah·Phase 1·NCT04106856·22 enrolled

Unspecified2 trials

Development of Minidose Inje Cocktail Method for Simultaneous Evaluating Five Cytochrome P450 Isoforms in Human

Completed·IInje University·Phase 1·NCT01570569·26 enrolled

Renin Angiotensin System Study (RASS/B-RASS)

Completed·—·Phase 2·NCT00143949·285 enrolled

Regulatory

FDA Approval Timeline[5]

Apr 14, 1995

COZAAR

NDA NDA020386

Apr 14, 1995

COZAAR

NDA NDA020386

Nov 22, 1995

COZAAR

NDA NDA020386

Dec 1, 1995

COZAAR

NDA NDA020386

Jul 18, 1996

COZAAR

NDA NDA020386

Aug 7, 1996

COZAAR

NDA NDA020386

Nov 7, 1997

COZAAR

NDA NDA020386

Feb 25, 1998

COZAAR

NDA NDA020386

Mar 9, 1998

COZAAR

NDA NDA020386

Mar 27, 1998

COZAAR

NDA NDA020386

Apr 3, 1998

COZAAR

NDA NDA020386

Aug 31, 1998

COZAAR

NDA NDA020386

Aug 31, 1998

COZAAR

NDA NDA020386

Aug 31, 1998

COZAAR

NDA NDA020386

Oct 13, 1998

COZAAR

NDA NDA020386

Nov 24, 1998

COZAAR

NDA NDA020386

May 13, 1999

COZAAR

NDA NDA020386

Jun 9, 1999

COZAAR

NDA NDA020386

Jan 19, 2000

COZAAR

NDA NDA020386

Jan 28, 2000

COZAAR

NDA NDA020386

Feb 23, 2000

COZAAR

NDA NDA020386

May 16, 2001

COZAAR

NDA NDA020386

Jun 22, 2001

COZAAR

NDA NDA020386

Jul 3, 2001

COZAAR

NDA NDA020386

Aug 24, 2001

COZAAR

NDA NDA020386

Oct 3, 2001

COZAAR

NDA NDA020386

Jan 10, 2002

COZAAR

NDA NDA020386

Sep 17, 2002

COZAAR

NDA NDA020386

Oct 23, 2002

COZAAR

NDA NDA020386

Mar 25, 2003

COZAAR

NDA NDA020386

Mar 11, 2004

COZAAR

NDA NDA020386

Mar 11, 2004

COZAAR

NDA NDA020386

Apr 12, 2005

COZAAR

NDA NDA020386

Apr 12, 2005

COZAAR

NDA NDA020386

Mar 31, 2006

COZAAR

NDA NDA020386

Aug 29, 2006

COZAAR

NDA NDA020386

Sep 21, 2006

COZAAR

NDA NDA020386

Sep 21, 2006

COZAAR

NDA NDA020386

Jun 5, 2009

COZAAR

NDA NDA020386

Sep 23, 2010

COZAAR

NDA NDA020386

Jun 10, 2011

COZAAR

NDA NDA020386

Nov 17, 2011

COZAAR

NDA NDA020386

Sep 28, 2012

COZAAR

NDA NDA020386

Mar 27, 2013

COZAAR

NDA NDA020386

Jan 17, 2014

COZAAR

NDA NDA020386

Feb 20, 2014

COZAAR

NDA NDA020386

Sep 29, 2014

COZAAR

NDA NDA020386

Dec 11, 2015

COZAAR

NDA NDA020386

Oct 12, 2018

COZAAR

NDA NDA020386

Oct 15, 2021

COZAAR

NDA NDA020386

Mar 13, 2025

ARBLI

NDA NDA218772

Jun 20, 2025

COZAAR

NDA NDA020386

Sources

References

[1]
ClinicalTrials.gov — 198 trial records for Losartan. U.S. National Library of Medicine, National Institutes of Health.
[2]
MedlinePlus Drug Information — Cozaar drug information. U.S. National Library of Medicine, National Institutes of Health.
[3]
ChEMBL — Losartan compound record. European Bioinformatics Institute (EMBL-EBI).
[4]
Open Targets Platform — Drug–disease associations for Losartan. EMBL-EBI & Wellcome Sanger Institute.
[5]
OpenFDA — FDA approval records (NDA NDA020386). U.S. Food & Drug Administration.
[6]
FDA Orange Book — Patent and exclusivity data for Cozaar. U.S. Food & Drug Administration.
[7]
SEC EDGAR — Organon and Co company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Mechanism of Action: Type-1 Angiotensin II Receptor Antagonist[3]
Modality: Small molecule[3]
Highest Phase: Approved[1]
Company: OOrganon and Co

Patent Landscape[6]

Patent Cliff

Oct 7, 2041

Earliest patent expiration — generic entry possible after this date

Patent #Expires

12156869Oct 7, 2041

11890273Oct 7, 2041

12605365Oct 7, 2041

Cozaar

Status by Indication[4][1]

Competitive Landscape

Expected Milestones

Q4 2026

Q1 2027

Trials by Indication[1]

Hypertension17 trials

ART10 trials

COVID-199 trials

Essential Hypertension8 trials

Nephropathy7 trials

Hypertensive7 trials

Marfan syndrome5 trials

Diabetic Nephropathy5 trials

Kidney Disease4 trials

Fibrosis4 trials

Fasting Conditions3 trials

Peritoneal Dialysis3 trials

Cystic Fibrosis3 trials

Chronic Kidney Disease3 trials

Pancreatic Cancer3 trials

Heart Failure3 trials

Kidney Transplant3 trials

Idiopathic Pulmonary Fibrosis2 trials

Renal insufficiency2 trials

Type 2 Diabetes2 trials

Atrial Fibrillation2 trials

Trial2 trials

Blood Pressure2 trials

Insulin resistance2 trials

Tics2 trials

Hypertrophic Cardiomyopathy2 trials

Interaction2 trials

Tachycardia1 trial

Oxidative Stress1 trial

Hyperuricemia1 trial

NASH1 trial

Microvascular Function1 trial

Advanced Solid Tumors1 trial

Peripheral Arterial Disease1 trial

Peripheral Neuropathy1 trial

Treatment1 trial

Total Joint Arthroplasty1 trial

Myocardial fibrosis1 trial

Neuropathy1 trial

Survival1 trial

Adiponectin1 trial

Emotional Processing1 trial

Chronic Hepatitis1 trial

Chemotherapy1 trial

Heart Disease1 trial

Lupus Nephritis1 trial

Acute Respiratory Distress Syndrome1 trial

Diabetes Mellitus1 trial

Insulin Sensitivity1 trial

IgA Nephropathy1 trial

Type 2 Diabetes Mellitus1 trial

ESS1 trial

Metabolic Syndrome1 trial

Hypoxia1 trial

Biomarkers1 trial

Fracture1 trial

Obstructive Sleep Apnea1 trial

Dilation1 trial

Ovarian Cancer1 trial

Head and Neck Squamous Cell Carcinoma1 trial

Cirrhosis1 trial

Post-Traumatic Stress Disorder1 trial

Non-Small Cell Lung Cancer1 trial

Attention1 trial

Endothelial Dysfunction1 trial

Clinical Trial1 trial

Vitamin D1 trial

Cardiovascular Disease1 trial

Ischemic stroke1 trial

Total Knee Arthroplasty1 trial

Arteriovenous Fistula1 trial

Cardiomyopathy1 trial

Adenocarcinoma1 trial