Saline
(Sodium Chloride)Small molecule
Sodium chloride is a salt solution used to clean wounds, flush eyes, and help your body maintain proper fluid balance. It's also given intravenously to treat dehydration and as a carrier for other medications.[1]
0
Indications
180
Total Trials
56
Active Trials
0
Competitors
38
FDA Applications
NDA/BLA/ANDA regulatory filings
Timeline
Expected Milestones
Clinical
Trials by Indication[1]
Nephropathy4 trials
COVID-194 trials
Stroke3 trials
Cardiac Arrest3 trials
Inflammatory Response2 trials
Nasal Immune Challenge Study
Active, not recruiting·CCambridge University Hospitals NHS Foundation Trust·Preclinical·NCT06021002·24 enrolled
143 more indications
Delirium2 trials
Fatigue2 trials
Hysterectomy2 trials
Dexmedetomidine2 trials
Erector Spinae Plane Block2 trials
Cystic Fibrosis2 trials
Acute Kidney Injury2 trials
Hyponatremia2 trials
Bupivacaine2 trials
Study : LEVOBUPIVACAINE Versus Placebo
Completed·—·Phase 3·NCT00621907·140 enrolled
General Anesthesia2 trials
Tonsillectomy2 trials
Humans2 trials
The Effects of Glucagon on Renal Regional Blood Flow in Humans Measured by Magnetic Resonance.
Not yet recruiting·—·N/A·NCT06872060·10 enrolled
Influenza2 trials
A Phase 1, Randomized, Controlled, Dose-Ranging Study to Evaluate the Safety and Immunogenicity of Influenza A Group 1 and Influenza A Group 2 mRNA Chimeric Hemagglutinin Vaccine Candidates Alone and in Combination in Healthy Adults.
Not yet recruiting·NNational Institute of Allergy and Infectious Diseases (NIAID)·Phase 1·NCT07703514·60 enrolled
Obesity2 trials
Hemodynamic Stability1 trial
Myasthenia Gravis1 trial
Ischemia1 trial
Paralysis1 trial
Popliteal Nerve Block1 trial
Efficacy and Safety1 trial
Cesarean Section1 trial
Dexamethasone in the Prevention of Post-spinal Paralytic Ileus After Cesarean Section
Recruiting·—·Phase 1/2·NCT05654649·90 enrolled
Atrial Fibrillation1 trial
Randomized1 trial
Low back pain1 trial
Adjuvant1 trial
Study of an HIV Preventive Vaccine Given With or Without an Adjuvant in HIV Uninfected Adults
Completed·NNational Institute of Allergy and Infectious Diseases (NIAID)·Phase 1·NCT00111605·144 enrolled
Osteoarthritis1 trial
Total Knee Arthroplasty1 trial
Hip Arthroplasty1 trial
Microvascular Function1 trial
Hyperlipidemia1 trial
Septic Shock1 trial
Balanced Crystalloid vs. Saline in Children With Septic Shock
Completed·—·N/A·NCT02835157·708 enrolled
Interstitial Cystitis1 trial
Household Contacts1 trial
Respiratory Failure1 trial
Agitation1 trial
Lidocaine Infusion1 trial
Effect of Intraoperative Lidocaine Infusion on Intraoperative Isoflurane Requirements
Completed·—·N/A·NCT03386565·50 enrolled
Bipolar Disorder1 trial
Effect of Regulated Add -on Sodium Chloride Intake on Stabilization of Serum Lithium Concentration in Bipolar Disorder
Completed·—·Phase 4·NCT04222816·60 enrolled
Tranexamic Acid1 trial
Chlorhexidine1 trial
ART1 trial
Infliximab1 trial
Myocardial Infarction1 trial
Kidney Transplant1 trial
Chronic Hepatitis1 trial
Age-Related Macular Degeneration1 trial
Systemic Avastin Therapy in Age-Related Macular Degeneration
Completed·TThe Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery·Phase 2/3·NCT00531024·30 enrolled
Postoperative Pain Management1 trial
Spinal Anesthesia1 trial
Pectoral Nerve1 trial
Infusion1 trial
Ophthalmologic Examinations After Infusion of ZK200775
Completed·—·Phase 1·NCT00999284·18 enrolled
Cirrhosis1 trial
Lumbar Degenerative Disease1 trial
Systemic Inflammatory Response Syndrome1 trial
Lidocaine1 trial
Pain With Trigger Finger Injection: A Comparison of Steroid Alone Versus Steroid/Lidocaine Mixture
Terminated·—·Phase 4·NCT02421419·26 enrolled
Orthopedic1 trial
Bronchiectasis1 trial
Randomised Controlled Trial1 trial
Intraoperative1 trial
Giant Cell Arteritis1 trial
Adductor Canal Block1 trial
Local1 trial
Blood Pressure1 trial
Prevention1 trial
Prevention of Spinal Induced Shivering During CS
Completed·—·Phase 2·NCT02588547·212 enrolled
After Cardiac Surgery1 trial
Preventing Acute Renal Failure After Cardiac Surgery in High Risk Patients Using Sodium Bicarbonate Therapy
Unknown status·MMcGill University Health Centre/Research Institute of the McGill University Health Centre·Phase 3·NCT00522756·200 enrolled
Immunogenicity1 trial
Botulinum Toxin1 trial
Sciatica1 trial
Ropivacaine1 trial
Concentration1 trial
Inguinal hernia1 trial
Growth1 trial
Sodium Supplementation and Growth in Very Low Birth Weight Infants
Terminated·—·Phase 4·NCT01795638·53 enrolled
Immunity1 trial
Lower Limb Surgery1 trial
Total Shoulder Arthroplasty1 trial
Parkinson's Disease1 trial
Pain1 trial
Postural Tachycardia Syndrome1 trial
Gonarthrosis1 trial
IUD1 trial
Ventilator-Associated Pneumonia1 trial
Emergence Agitation1 trial
Dermatitis, Atopic1 trial
Amyotrophic Lateral Sclerosis1 trial
A Randomized, Double-blind, Placebo-controlled, Multicenter Clinical Trial Evaluating the Safety, Efficacy, and Pharmacokinetic Characteristics of TP04HN106 in the Treatment of Patients With Amyotrophic Lateral Sclerosis
Recruiting·TTalengen Institute of Life Sciences, Shenzhen, P.R. China.·Preclinical·NCT06726577·60 enrolled
Migraine1 trial
Tachycardia1 trial
Insulin resistance1 trial
Alcohol Use Disorder1 trial
Dry Eye1 trial
Overweight and Obesity1 trial
Aortic dissection1 trial
Post Operative Pain1 trial
Thyroid Disease1 trial
Laparoscopic Cholecystectomy1 trial
Atopic Dermatitis Eczema1 trial
Ketamine1 trial
Surgical1 trial
Psilocybin1 trial
Digestive System Disease1 trial
Hip Fractures1 trial
Wound1 trial
Lipoprotein Disorder1 trial
Pain, Neuropathic1 trial
Mild to Moderate Hypertension1 trial
Anorexia Nervosa1 trial
Suicide, Attempted1 trial
Arthroplasty, Replacement, Hip1 trial
Pain Management1 trial
Hypotrichosis1 trial
Hip Osteoarthritis1 trial
Pain, Postoperative1 trial
Trauma Injury1 trial
Unspecified7 trials
Proximal Lower Limb Intramuscular Block : Effects on Hemiparetic Gait
Unknown status·—·N/A·NCT05519592·30 enrolled
The Letrozole Administration During Luteal Phase
Unknown status·TThe Affiliated Hospital of Inner Mongolia Medical University·Phase 3·NCT02686151·50 enrolled
Show 4 more trials
Regulatory
FDA Approval Timeline[3]
Jan 1, 1982
SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER
NDA NDA017514
Jan 1, 1982
SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER
NDA NDA018314
Jan 1, 1982
SODIUM CHLORIDE IN PLASTIC CONTAINER
NDA NDA018247
Jan 1, 1982
SODIUM CHLORIDE
NDA NDA017038
Jan 1, 1982
SODIUM CHLORIDE 0.45% IN PLASTIC CONTAINER
NDA NDA018503
Jan 1, 1982
SODIUM CHLORIDE
NDA NDA017013
Jan 1, 1982
SODIUM CHLORIDE 0.45% IN PLASTIC CONTAINER
NDA NDA018090
Jan 1, 1982
SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER
NDA NDA017464
Jan 1, 1982
SODIUM CHLORIDE 0.45% IN PLASTIC CONTAINER
NDA NDA018016
Jan 1, 1982
SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER
NDA NDA016366
Jan 1, 1982
SODIUM CHLORIDE 0.45% IN PLASTIC CONTAINER
NDA NDA018184
Jan 1, 1982
SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER
NDA NDA018502
Jan 1, 1982
SODIUM CHLORIDE 0.45% IN PLASTIC CONTAINER
NDA NDA017864
Jan 1, 1982
SODIUM CHLORIDE 0.45% IN PLASTIC CONTAINER
NDA NDA017670
Jan 1, 1982
SODIUM CHLORIDE 0.45% IN PLASTIC CONTAINER
NDA NDA018380
Jan 1, 1982
SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER
NDA NDA016733
Jan 1, 1982
SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER
NDA NDA017427
Jan 1, 1982
SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER
NDA NDA017867
Feb 19, 1982
SODIUM CHLORIDE 0.45% IN PLASTIC CONTAINER
NDA NDA018497
Oct 29, 1982
SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER
NDA NDA018803
Oct 29, 1982
BACTERIOSTATIC SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER
NDA NDA018800
Nov 1, 1983
SODIUM CHLORIDE 3% IN PLASTIC CONTAINER
NDA NDA019022
Jul 13, 1984
SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER
NDA NDA019218
Jul 20, 1984
SODIUM CHLORIDE 14.6%
NDA NDA018897
May 17, 1985
SODIUM CHLORIDE 0.9% IN STERILE PLASTIC CONTAINER
NDA NDA019319
Jul 15, 1985
SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER
NDA NDA019465
Sep 17, 1985
SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER
NDA NDA019480
Oct 30, 1985
SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER
NDA NDA016677
Apr 22, 1987
SODIUM CHLORIDE 23.4% IN PLASTIC CONTAINER
NDA NDA019329
Mar 9, 1988
SODIUM CHLORIDE 0.45% IN PLASTIC CONTAINER
NDA NDA019635
Jun 8, 1988
SODIUM CHLORIDE 0.45% IN PLASTIC CONTAINER
NDA NDA019759
Sep 3, 1992
BRONCHO SALINE
NDA NDA019912
Dec 7, 1992
SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER
NDA NDA020178
Nov 18, 1998
SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER
NDA NDA019217
Jul 27, 2006
SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER
NDA NDA021569
Jan 6, 2012
SODIUM CHLORIDE 0.9%
NDA NDA202832
Oct 8, 2020
XENLETA
NDA NDA211673
Mar 16, 2021
XENLETA
NDA NDA211673
Sources
References
- [1]
- [2]
- [3]
- [4]
Details
Drug Info
Quick Facts
- Modality
- Small molecule[2]
- Company
- MMilestone Pharmaceuticals Inc.